|Croscarmellose sodium is used in oral pharmaceutical formulations as a disintegrant for capsules, tablets, and granules.
In tablet formulations, croscarmellose sodium may be used in both
direct-compression and wet-granulation processes. When used in wet
granulations, the croscarmellose sodium should be added in both the wet
and dry stages of the process (intra- and extragranularly) so that the
wicking and swelling ability of the disintegrant is best utilized.